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Re: Tucatinib Is Active Against Brain Metastases in HER2+ Breast Cancer
Imteresting.
One thing about Tucatanib surprised me when I looked at the package insert. It can cause severe diarrhea. When it first was being researched they didn't think it would because it wasn't supposed to inhibit the epidermal growth factor receptor, just the Her 2 neu receptor. Still the fact that it is effective against brain mets is exciting news.
Other Tukasyn side effects are liver damage (possible) fatigue. hand foot syndrome, anorexia and stomatitis, vomiting and diarrhea The dose is 300mg every 12 hours.
Paul
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