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Old 01-03-2019, 03:03 PM   #1
tricia keegan
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Re: Two Chemo drugs linked to BC spread

Cutiepie, I would have disregarded this out of hand straight away, if it were true it would be huge news and in every newspaper and on news tv show. I also had these meds and while they can certainly leave us with some side effects we're both years out from cancer and that is worth the risk to me. As we age we do have bone issue's regardless of cancer or not, I'm sure genes come into that in a huge way. I took hormone therapy for ten years too and felt no better when I stopped, my aches were simply old age catching up with me although I am very active and walk ninety minute's every day. Chemo is not perfect but it's the best we have, the risks were explained to me and I took them and would do the same tomorrow. However I don't believe for a minute that the drugs I had cause cancers to spread and it's a shame we don't have a link to the article but I really would'nt wowrry about it.
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 01-03-2019, 03:11 PM   #2
Becky
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Re: Two Chemo drugs linked to BC spread

https://www.nature.com/articles/s41556-018-0256-3
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 01-03-2019, 03:19 PM   #3
Becky
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Re: Two Chemo drugs linked to BC spread

It was just published in Nature this month. It is specific to getting chemo before surgery. You can't read the whole article but the abstract is specific about they have tons of work to do to see if there is a relationship generally.

Sometimes studies are done and it is relevant to a certain population of patients and not all patients. For example, Herceptin almost was not marketed because the first studies showed no statistical improvement because they tried it on some women who were not Her2+ so it didn't work too well. This may be significant to a population of very specific women who should get their tumors removed first and then get chemo as they did back in our day. Now they give chemo first then remove the tumor.

Everyday we get a little bit closer! Cure!
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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