Anyone switch from Arimidex to tamoxifen?

[donocco]

Dee

Trying a different Aromatase Inhibitor is an option. If the oncologist decides on Tamoxifen you have to be aware that Tamoxifen is an inactive prodrug. It becomes an active drug, Nor-Tamoxifen in your body using an enzyme called Cyp-2D6. Drugs that inhibit this enzyme prevent the formation of this active form.

There are a lot of these drugs but many of the anti-depressants ie Prozac (Fluoxetine) Paxil (Paroxetine), and Wellbutrin (Bupropion) do this. So does Quinidine but Quinidine is a heart drug and I doubt you would be taking this.


Paul