Cool. Well, that's my impression. I'm glad they are learning new things.
A gal with brain mets on breastcancer.org tested positive for PI3KCA, something associated with a non-PCR and possible resistance in HER2+ patients.
There might be ways to overcome the resistance but it will take other drugs and also patient-driven alternative treatment additions to move the needle so to speak. Standard of care gets stuck but with hyperbaric oxygen, water-based fasting, IV curcumin, and other supplements that cancer metabolism might be altered.
Some links:
Network of PIK3CA mutations may affect response to HER-2–targeted therapies
http://www.healio.com/hematology-onc...eted-therapies
Cell Death and Disease - Clinical update on cancer: molecular oncology of head and neck cancer (Scroll halfway down for suggestions for ways to shift resistance)
http://www.nature.com/cddis/journal/...s2013548a.html
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