TDM1 for HER2+ brain mets reocurrence?

[Rolepaul]

That case was actually run under Dr. Slamon. I contacted her mother in October of 2011. The woman has some short term memory issues, with the need to make a list of everything she needs to do for the day and a good outlook calendar. WBRT has a wide range of cognitive effects that we chose not to risk. Some are minimal and it seems there is no impact. Others are no longer able to work or even look after children due to inability to remember and focus. I am fairly aware of the cases and progress that have been done at this point.
Northwestern was running a lower dose than we wanted to do. Dr. Razier was not willing to change the dose, so we made our own compassionate care mini clinical trial. Not many could make that happen three years ago, but we had the right educational background to make it work.
Nina's case is still in discussion. It had two papers published referencing the work as a sidebar. It has gone to San Antonio Breast Cancer Conference twice for discussion that we are aware of. It will always be the MD Anderson Cancer Center case by Nina's choice.