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Old 03-31-2015, 01:18 PM   #1
Rosalie
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Join Date: Dec 2014
Posts: 18
Re: HER-2 Positive & Triple Negative = Cannabis Intervention

This is an area my sister and I are excited about! From what we've understood, it's important for the oil (you have to eat the oil not smoke it) to have near equal amounts of THC and CBD.

There's a phase 2 trial about to start in Israel testing the effects of cannabinoids on cancer in humans: https://clinicaltrials.gov/ct2/show/...&sel_rss=mod14

Here’s all of the other research I know about.

Breast-cancer specific:

August 2011 research from Dr. Sean McAllister on cannabidiol (CBD) inhibiting the spread of breast cancer.
http://www.medscape.com/medline/abstract/20859676
(More on McAllister and his research here.)

A 2010 study on cannabinoids specifically targeting her2
http://www.molecular-cancer.com/content/9/1/196#B4

A February 2006 study found anandamide (a cannabinoid neurotransmitter) inhibited the spread of breast cancer cells.
http://www.ncbi.nlm.nih.gov/pubmed/16343481

A 2011 study on the effect of cannabinoid on chemokine receptor CXCR4: http://www.ncbi.nlm.nih.gov/pubmed/2...?dopt=Abstract

2007 research by McAllister and Desprez -Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cell
http://www.ncbi.nlm.nih.gov/pubmed/18025276


Specific to other cancers:

1974 University of Virginia study found that tetrahydrocannabinol (THC) slowed Lewis lung adenocarcinoma and leukemia growth in a dose-dependent relationship: http://www.ncbi.nlm.nih.gov/pubmed?c...t_uids=1159836

1998 study from Dr. Manuel Guzmán showed THC induced apoptosis in glioma cells: http://www.ncbi.nlm.nih.gov/pubmed/9771884

A 2006 study by Dr. Manuel Guzmán found that THC could induce apoptosis in multiple pancreatic cancer cell lines: http://cancerres.aacrjournals.org/co...6/13/6748.full

A 2007 Harvard Study demonstrated THC inhibited multiple non-small cell lung cancer lines and reduced tumor weight and volume in mice by 50%.
http://www.ncbi.nlm.nih.gov/pubmed/21097714

A 2003 study showed activation of cannabinoid receptors induced skin cancer cell death: http://www.jci.org/articles/view/16116

1999 study in FEBS Letters found THC induced apoptosis in the PC3 line of prostate cancer: http://www.ncbi.nlm.nih.gov/pubmed/10570948

A 2011 study of the effects of THC on apoptosis in prostrate cancer.
http://www.ncbi.nlm.nih.gov/pubmed/22110202

June 2003 study demonstrated anandamide (a cannabinoid neurotransmitter) induced apoptosis in multiple prostate cancer cell lines.
http://www.ncbi.nlm.nih.gov/pubmed/12746841

October 2013 research at the University of London, St. Georges, showed that cannabinoids could kill leukemia cells.
http://ar.iiarjournals.org/content/3...ract#corresp-1

November 2013 study published in Case Reports in Oncology offers proof that cannabis extracts may be able to kill cancer in a human body.
http://www.karger.com/Article/FullText/356446

A November 2006 study found that liver cancer patients with higher expressions of CB1 and CB2 cannabinoid receptors had much better disease-free survival than patients with lower expressions.
http://www.ncbi.nlm.nih.gov/pubmed/17074588

November 2014 study showing that cannabinoids CBD and THC could shrink aggressive brain cancer.
http://mct.aacrjournals.org/content/...-0402.abstract
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