Is THIS the reason adding herceptin to chemo only improves OS by 40%?

[Lani]

linn65--they only look for what is requested by the doctor ordering the pathology examination with report and only with the means requested

eg, if IHC (immunohistochemistry) is requested and only ER PR and her2 are checked of, those are the only stains utilized and those the only items reported

if FISH is ordered(or ordered only if her2 2 and above) for her2, that is reported

As regards "cotton candy" it has only now been reported to be potentially so important. If these findings are corroborated by others we may see the test for "cotton candy" added to the list to be checked off for tests the pathologist should run and maybe it will become standard of care to add a monoclonal antibody to "cotton candy" to herceptin to the treatment of those whose her2+ tumors that have enough of it