Finally!!!!! a paper showing which tumor markers (and serum her2ECD test) are best at

[Lani]

PS

I have been hoping to get a researcher interested in validating the serum her2 ECD test in CSF in order to follow how IT herceptin treatment is working, determine the optimal dosage and administration and combinations etc.

If anyone with leptomeningeal mets under treatment has a doctor who might be interested in this, please let me know. The tests kits for about 28 patients will cost $1000 and before the test begins they will need some samples of CSF from patients without brain mets (ie from a researcher working on something else or a clinician who has to draw CSF to do myelograms, rule out MS etc) to be sure there is no problem using the test on CSF in general. Here too advocacy could help push a project along which might help those brave volunteers like Courtney who just tried the dosage/administration schedule that had been done in a handful of cases before. Perhaps we might also find that we could diagnose her2+ brain mets as well as lm mets early if lumbar punctures are performed before symptoms occur in those at high risk, as we know that catching brain mets early when they are small and few DOES make a difference with allowing SRS to be performed rather than WBR.