Intrathecal Herceptin/Topotecan for Leptomeningeal Disease

[evlin75]

Susan had a few uncomfortable days after her last treatments - some vomiting.

She had the IV treatment of herceptin and perjeta and then the next day the intrathecal treatment of herceptin and toptecan. She needs to separate the treatments in the future and NOT do them back to back.

The cardiologist cleared her completely by EKG and ultrasound. Said she had a healthy heart. That is very good news all around as she can now have the ommaya replaced and it also indicates the Herceptin in the larger doses is not harming her heart.

Her doctor gave her the 80 mg today. That is the dose recommended according to the 1.5 mg per kg of body weight. She sees the neurosurgeon again tomorrow to begin again the process of setting up the ommaya surgery replacement. The cardiologist expressed shock that they canceled the former surgery scheduled since he found no problems.

I am relieved. Her next MRI is next Tuesday.

Ev