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Old 09-08-2012, 04:20 AM   #1
Becky
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Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
Re: Is there benefit in surgery for stage iv's

Herceptin and most chemo are large molecules and cannot cross the blood brain barrier.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 09-08-2012, 04:41 AM   #2
chrislmelb
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Join Date: Sep 2005
Location: melbourne, australia
Posts: 267
Re: Is there benefit in surgery for stage iv's

Vonny i canunderstand wanting to get the lump out. I think they leave it to use as an indicator to see if the treatment is working.
This might be a dumb question to everyone but what has the spine got to do with BBB? Is it if the cancer goes thru into the bone marrow? I have numerous spinal mets so left wondering.
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Christine

DX Sept 03 age 40 Stage 2B Grade 3 mastectomy (after 2 prior breast conserving surgeries)
"at least" 2.3 cm 3/12 nodes ER+/PR+ Her2+++
8 FEC. Tamoxifen then Arimidex. Ovaries out.
"late" Herceptin for 2 years (18months after chemo) on HERA trial. finished Herceptin Nov 2007.
Multiple bone mets May 2012 and now liver August 2012.
Abraxne, Herceptin and Zometa.
June 2013 Tykerb, Xeloda and Xgeva
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