Herceptin / Tykerb Share your experiences or ask questions about Herceptin or Tykerb |
|
08-22-2011, 03:46 PM
|
#1
|
Senior Member
Join Date: Jun 2011
Location: Iowa
Posts: 231
|
Ca27.29#s and NED at stage IV
Stage IV ladies,
For those of you lucky few who have become NED after a stage IV diagnosis, what were your Ca27.29 values before and after you became NED? Thanks!
__________________
[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
|
|
|
07-29-2012, 09:56 AM
|
#2
|
Member
Join Date: Jul 2012
Posts: 9
|
Re: Ca27.29#s and NED at stage IV
Marker was 85...now 22.0 after treatment
|
|
|
07-29-2012, 12:24 PM
|
#3
|
Senior Member
Join Date: Oct 2005
Location: Lakeville, Minnesota
Posts: 199
|
Re: Ca27.29#s and NED at stage IV
Mine was 50 when I was diagnosed with liver mets. I have been NED for 17 months and during this time mine fluctuates between 9 and 17.
Laurie
__________________
diagnosed stage 2- 3/2005
4.5 cm & 2+ nodes , er/pr- & HER2+
4 AC
12 taxol/Herceptin
Year of Herceptin
liver mets- July-2010
7 taxotere/Herceptin
RFA- Feb.2011
NED
U of Wa vaccine trial-oct 2011-Feb 2012
Herceptin/tykerb
Ned - 2 1/2 years
Herceptin & perjeta
Ned 3 years
Herceptin- reducing treatments , due to s/e, to 5-6 a year
NED- 3 1/2 years
Ned - 4 years
2/15- stopped herceptin - on no treatment
|
|
|
07-29-2012, 12:55 PM
|
#4
|
Senior Member
Join Date: Jan 2012
Location: Boulder Colorado as of January 2013
Posts: 391
|
Re: Ca27.29#s and NED at stage IV
44 now 26.
|
|
|
08-08-2012, 07:52 PM
|
#5
|
Senior Member
Join Date: Mar 2012
Location: New York, new york
Posts: 73
|
Re: Ca27.29#s and NED at stage IV
Marker was 87, started tykerb 6 pills a day with herceptin every 3 weeks in march 2012...tumor marker, now in jul is 38 and pet scan is better
|
|
|
08-17-2012, 06:37 PM
|
#6
|
Senior Member
Join Date: Jun 2011
Location: Iowa
Posts: 231
|
Re: Ca27.29#s and NED at stage IV
Thanks ladies- I guess I was hoping that there were some out there like me. My tumor marker is in a semi-stable or very gradual rise, sitting right around 120. I read way too much into that damn number, I feel great! I go jogging, I sew, I cook, I have a totally normal life (despite taking ibuprofen due to femara aches and pains)- why am I so obsessed with seeing that number drop. Sometimes I wish he wouldn't tell me what that God-damned number is.
Thanks Ladies.
__________________
[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
|
|
|
08-17-2012, 09:58 PM
|
#7
|
Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
|
Re: Ca27.29#s and NED at stage IV
At liver mets diagnosis CA 27-29 was 57. I began treatment and it went up as far as over 100 before coming back down into normal range.
Since meeting up with NED that number has been between 17 and 23 normally, with an occasional spike into high 20's that goes right back down.
Have you ever had the HER2 serum Elisa checked? Mine goes between 7 and 10.
Can't explain why you have a higher than normal range number.
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 06:46 PM.
|