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I had chemo which included Herceptin before surgery. I had to stop all treatemnt before surgery and then after surgery I started Herceptin and Radiation. I continued Herceptin until it affected my heart function. I am now 3 years out of treatment and I'm doing great. My surgeon told me that they did not know if Herceptin would increase any problems with blood clotting factors at the time of surgery and it would be best to not have it during that time. I think that there is just so much that they don't know that they don't want to take a chance. All I know is that being off Herceptin and then going back on did not seem to be a risk or a problem.
Alice
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