Tykerb stopped working

[Joy]

Julie, I really understand your frustration and pain, emotional that is. Just when some of our hopes and dreams are coming true-cancer reaches in and sucks some of the joy out of it. It makes me angry for all of us. I have shed many tears in the dark over that. It makes you wonder if we should pursue anything at all in the dark times. I am so sorry about this phase of things for you.

But, I do think some of our resident sages, yourself included, have offered some good advice and experience as well as questions to pursue with your medical team. We have to believe that there is always something else. It is a hard hope to have when you see the word 'progression' over and over again. But there are things out there and the DM1 trial could be a great option for you among several.

Continue to hope and to fight. Be mad and frustrated too when you need to. I know how exhuasting it is.

I know you will find the route you need to take and I am hoping it is effective and fairly easy to take. Being in Texas is a good thing too as was mentioned. As Will Ferrel said in "Blades of Glory": "work the google on your internet machine," and find the trials that apply to you and ask, ask, ask all the questions you can.

[julierene]

I live in DFW. I just got back from the onc, and my liver mets got a little better, my bone mets got worse, and my tumor marker went up. So he wants to go back on Herceptin/Carboplatin/Taxol. If my insurance will allow it, he is going to substitute the Taxol with Abraxane. That should help with toxicity. Anyway, I don't know how I feel about going back to an old treatment that worked, but if it doesn't help, he wants to go to Avastin + chemo. Any thoughts?

I feel so down right now, I just wanna tell the guy I just started seeing that he would be better off without me. I know that's not right, he's been single too much. But it just doesn't seem fair to him at all.