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Old 12-16-2007, 08:42 AM   #1
tousled1
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Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
Donna,

Sorry to hear about your progression. I'm on Taxol/Carboplatin/Herceptin for lung mets. My last scan showed some improvement. Side effect I'm having is severely dropping of counts. Right now I'm taking a break from chemo and will resume after the Holiday and my scan.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 12-16-2007, 11:28 AM   #2
Julie2
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Donna,

Sorry to hear the news about progression. You can also try for Herceptin-MCC-DM1 trial or the Heat shock protien trial. Whatever you decide may your outcome be wonderful and keep you in remission.

Julie
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Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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Old 12-16-2007, 01:39 PM   #3
LOPSIDED
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Join Date: Apr 2006
Location: FLORIDA
Posts: 148
I CAN RELATE. FOR THE LAST 9 MONTHS ALL I HAVE BEEN DOING WAS GETTING FASLODEX SHOT. I WENT FOR CT SCAN AND IT SHOWED ENLARGED LYMPH NODES. I GO BACK TO CHEMO THIS COMING TUESDAY. MY DOC IS STARTING ME ON A NEW DRUG CALLED IXABEPILONE (IXEMPRA). IF IT WORKS I WILL ALSO START TYKERB. I WILL PRAY YOU FIND A NEW COMBO THAT WORKS FOR YOU
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SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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Old 12-17-2007, 08:56 AM   #4
doh2pa
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Location: Chadds Ford, Pa
Posts: 206
Hi All,

Thanks for your encouragement and information. You ladies are wonderful.

As far as the practical advice, I was on ixabipelone with carbo and herceptin for 6 months. It totally knocked those liver mets out and I was free and clear for 6 months - so I would highly recommend that combo to anyone out there with liver mets. Still waiting for the onc to return my call to see what he recommends. I will keep you all posted.

Just another curve ball.......
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Donna
Diagnosed 2/04 - Invasive ductal - no clean margins
node negative - er+pr+, her2++
Mastectomy 4/04 - 4 rounds AC
9/05 - mets to liver treated with carbo/ixabipelone/herceptin
3/06 - complete remission
9/06 - new liver mets, starting Taxotere/Herceptin
1/07 -Liver mets stable, staying on Herceptin
5/07 - Liver, lung progression - starting T/X
12/07 - Liver, lung progression - starting weekly Navilbene/Herceptin
4/08 - Liver progression - started Abraxane, Carbo, Tykerb and Herceptin
7/08 - Liver Progression - started Gemzar, Avastin and Tykerb
10/08 - Liver progression - starting Doxil
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