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10-22-2009, 07:58 PM
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#1
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Senior Member
Join Date: Feb 2008
Location: South East Wisconsin
Posts: 3,431
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Scan choices: Is there a radiologist in the house?
So..mom has mets to liver and lung. She had a PET/CT early June which showed mostly inactive liver mets but significant uptake in one of the lung nodules. Been following stubborn lung module with CT late June and early September and it's time for another scan. I have found articles about benefits of tracking chemo efficacy with PET/CT. The doc thinks CT would be more apples to apples with last scan but I know it wouldn't tell much about the liver activity or whether uptake is less in lung nodule. My sense so far is that dedicated CT is better than the non-contrast, low dose cT included in a PET/CT. To complicate things, they want mom to skip contrast in the next CT due to perceived reactions to the contrast.
So...
I'm leaning towards PET/CT giving more overall information than non-contrast traditional chest and ab CTs. But if CT w/o contrast is still measurably superior in terms of tracking the lung nodule absolute size, that might sway things...though that would not say anything about activity in liver or change in uptake which can precede size changes.
One option might be to have insurance pay for the more expensive (eye to thigh) PET/CT and if lung nodule is equivocal, pay for a less expensive chest CT for clarification.
Thoughts?
They are also wanting a mammo..which surprised me given the state of things.
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10-23-2009, 12:54 AM
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#2
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Senior Member
Join Date: May 2006
Location: Haarlem, the Netherlands
Posts: 835
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Re: Scan choices: Is there a radiologist in the house?
There 's a nuclear medicine tech on the breastcancer list who sometimes answers people's questions about scans and such. She's not a doctor, but she's experienced and a great person with a wonderful sense of humor. Her name is Toya. She may have some suggestions for you.
You can find the list on: www.bclist.org
There are archives you could browse at http://bclist.petebevin.com/
Look for Toya the nuke nut.
Jacqueline
__________________
Diagnosed age 44, January 2004, 0.7 cm IDC & DCIS. Stage 1, grade 3, ER/PR pos. HER2 pos. clear margins, no nodes. SNB. 35 rads. On Zoladex and Armidex since Dec. 2004. Stopped Zoladex/Arimidex sept 2009 Still taking mistletoe shots (CAM therapy) Doing fine.
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10-24-2009, 04:21 PM
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#3
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Senior Member
Join Date: Oct 2007
Posts: 1,851
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Re: Scan choices: Is there a radiologist in the house?
Rich,
Since there's significant uptake in the lung as shown via PET/CT, I would opt for the same test in following up. Also, since all PET/CTs are C1 to thigh, you'll get information on liver, bones and nodes, too, in terms of lighting up (I've never heard of a PET/CT being less than that).
The safe benchmark for lesions showing up on PET/CT is 1 cm, even though they could possibility light up if a cancerous lesion was under that size.
Joan
__________________
Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2023 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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10-24-2009, 05:16 PM
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#4
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Senior Member
Join Date: Jan 2008
Location: "Love never fails."
Posts: 5,809
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Re: Scan choices: Is there a radiologist in the house?
Rich,
I haven't had a PET since the recurrence was found in 2007. (Forced Onco for one in May 2008. So far nobody has offered to give me another one) There is a trend - according to the new ASCO guideline - discouraging PET use because it does not improve survival rate.
It does sound rediculous, but I think that's probably why her doctor is only prescribing CT.
Sending prayers from Central Texas.
__________________
Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2
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Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
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1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement (600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.
1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa
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Last edited by Jackie07; 10-24-2009 at 06:40 PM..
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10-24-2009, 05:58 PM
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#5
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Senior Member
Join Date: Feb 2008
Location: South East Wisconsin
Posts: 3,431
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Re: Scan choices: Is there a radiologist in the house?
Got a call back on this.
Turns out it took them a bit to come to the same conclusion: Since she won't be getting contrast with the CT("allergy"), it wouldn't have as much morphological advantage over the PET/CT to outweigh the added uptake information of the latter.
I wonder if the supposed lack of survival advantage applies to those with liver mets, since they (and necrosis) can be diffuse to the point of making CT indeterminate.
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10-24-2009, 06:34 PM
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#6
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Senior Member
Join Date: Feb 2006
Posts: 1,014
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Re: Scan choices: Is there a radiologist in the house?
I have PET/CT's done every 6 months to make sure everything is OK. That's what I would feel comfortable with if I were you. ..sherryg
__________________
Sherry
Diagnosed: December , 2005 at age 44
13+ positive lymph nodes
Stage IV , Her2+, 2 small mets to lungsChemo Started: Jan, 2006
4 months Taxotere, Xeloda, Hercepin
NED since April 2006!!
36 Rads to follow with weekly Herceptin indefinately
8 years NED now
Scans every year
Life is not about avoiding the thunderstorms, it's about learning to dance in the rain!
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