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Old 08-06-2006, 08:05 PM   #1
libby
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Join Date: Aug 2006
Posts: 1
Herceptin Side Effect

I am new to this forum in regards to posting a message but have been reading the message board for sometime and have learned a lot from many.
I was reading the topic on Herceptin side effects. I have been on Herceptin since April. Finished Taxol on June 29th. I continue to struggle with pitting edema in the feet and ankles. My onc tells me it is residual from the taxol however, I am really starting to think it is the herceptin after reading the post on side effects. I know it is a small price to pay but I was just wondering what others may be doing about it. Diuretics didn't seem to help and I don't care to be relying on those. It gets so bad some days I have trouble walking.
I will say sleeping hasn't been a real issue. I don't sleep as well as I use to but that has been tolerable.
So, anyone out there with the magic answer to the edema?
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Old 08-06-2006, 08:23 PM   #2
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Headaches, too...

Dear John,
There have been several discussions in the past month or so of sinus headaches as a side effect of Herceptin. Several members have experienced these, ranging from mild to severe. That said, with Her2 disease liking to metastasize to the brain, it's always important to get any persistent headaches checked out with an MRI. Several members have taken this precaution and had "clear" MRI's which is GOOD, but having to live with the headaches is not fun.
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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