Small Tumour & Herceptin Studies

[RobinP]

Note the above rates that I posted for relapse were from the Hera trial where tumor size was at least, from what I THINK- please check yourself to be certain, 2cm or node positive.In other words, the hera trial relapse results can be misleading for someone with a small- under 2cm and node negative her2+bc. Still, it does say something about how much more aggressive hormonal negative her2+ bc is compared to hormonal positive her2+ bc.

[atdec05]

Hi Robin,

I think those recurrence rates apply to stage 1 as well, because those numbers are what my onc. told me. Basically, other than being early stage, all my tumor characteristics were agressive, fast-growing, and I was pre-menopausal. So that's why I went for the chemo.

Of course, only later trials will pinpoint how long we really need to take Herceptin. The Finnish test is promising, but it was done on a small group of women.

[RobinP]

Yes, it would be nice to have a larger study trial.Still, the 9week FINHER trial, albiet small, does say something and the study size was over 120, i believe, making it have statistical significance. Also, the Hera trial did have actually longer follow-up than the HERA and NCI adjuvant trials.