Are most of us with Grade 3 Tumors?

[AlaskaAngel]

So I wonder how long it would take for us to each be reclassified by the new criteria and after that, how long it would be before it would actually change therapy for any of us...

Especially those who are NED, since treatment never changes for those who are NED until we recur.

The theory about dormant cells in the bone is interesting, given that there is evidence that even most patients with early stage bc are found to have micromets in the bone.

It seems logical to me that if it is true that even most early stage patients have micromets to the bone, the least they could do for any NED HER2+++ who is more than a year out would be to sample for bone micromets -- and if they find them, then they should make it standard practice to prescribe Herceptin so that our insurance will pay for it. (Does this seem like rocket science to anybody?)

To answer the question, I too was Grade 3 (SBR 8-9).

AlaskaAngel

[StephN]

It would seem that the answer to the initial question is "yes."

All my Pathology reports say that the tissue they examined is HIGH grade. This is from 2000, so I imagine would be called differently now.

I was postmeno, but the tumor was advancing through my nodes in breast and lower right axilla.

They also say: Mitotic rate - high (but no number)

The salient point in my consultations was that I was HIGH risk for recurrance, which warranted more aggressive than usual treatment from the outset. That did little to slow things down!

[Montana]

My IDC was Stage 1; grade 2 and SBR was 7/9. The DCIS was high grade with comedo necrosis. Her2+ of 3.6 on ICH and high KI-67. No nodes and .6 cm. Post-meno. I finished A/C x 4 and 33 rads treatment in June 05 and did not receive herceptin as onc said no nodes and only 9% chance of recur.
I'd like to be test for the bone micromets so I could quit thinking about recurrence all the time.