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I got that rash too on the q3week dose of Herceptin-the weekly dose didn't do the same thing. I had little bumps all over my torso, back of shoulders, back of arms. It eventually went away, along w/the major all-over-body arthritis pain...just in time for the next q3week dose. Benadryl didn't seem to help, but I guess it's worth a try...Good luck!
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