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I did the 12 weekly Taxols - was on trial but didn't get Herceptin. The weekly Taxol was OK - I had aches and pains, sort of flu-y feeling 2/3 days after treatment for about 3 (sometimes 4) days. It was an out of sorts feeling rather than agonising pain. I had neuropathy of toes and a bit on my fingers. Nails go weird, and are still working out their strange colour. I didn't lose any nails though. I didn't have the queasy feeling I had on AC, and also didn't have that horrible everything smells so bad thing. Had no mouth sores. My red counts went low, and I was given Procrit for most of the 12 weeks. I felt tired on and off. Really not too bad, and from everything I've heard I think the weekly is a tad easier to deal with than the 2 or 3 weekly. I have heard that the risk of neuropathy is a bit higher with the weekly, but the chemo nurses will watch for that. Be warned they'll pump you with Benadryl before the first few sessions to prevent allergic reaction - I went out like a light for the first session (which was a double Benadryl dose) and had to fight to keep eyes open for 2nd and 3rd (lesser dose), but after that they stopped the Benadryl. Strange to say the time I was getting Taxol was almost the most relaxing time of my week - I could legitimately sit back for a couple of hours, watch tv or just go blank for a bit. I worked through all the treatment and was quite ready for a bit of a rest at that point! Good luck.
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