MM-302: HERMIONE study

donocco · 06-09-2016, 02:35 PM

Im delighted to be mistaken.Years of pharmacy practice have made me too cynical. I hope this MM-302 is a breakthrough

As far as Tofacitinib is concerned it is a Stat 3 inhibitor that is being investigated for various cancers. Ill have to do some research on both. When I had my own pharmacy way back when a pharmacist would call me and say "Guess what Paul they are coming out with a Zofran SR or whatever. Nothing more was said. It was understood that Zofran or whatever was going generic. In those days the generics were priced much lower than the brands. Now shamefully the price charged for the generics are skyrocketing.

Glad to be mistaken

Paul

michka · 06-10-2016, 01:25 AM

Thank you Joan for sharing this information. I am always happy to see your posts and admire that you are so active at Asco! I hope you are well.

Lani · 06-10-2016, 12:08 PM

So Cal Gal--the chemo part of TDM-1 is a maytansinoid not an anthracycline.

Has a somewhat different mechanism of action. Sorry to be so picky, but I didn't want someone to say they failed on anthracyclines when asked if they failed on tdm1, as that might keep them from being offered some alternatives they might otherwise be eligible for.