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Old 06-01-2016, 04:06 PM   #1
Juls
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Join Date: Mar 2014
Location: UK
Posts: 563
Re: My Onc wants to stretch out Herceptin infusions

Hi Jocanuck
Not sure if it would. Radiation has never been mentioned but bone met now sclerotic so all they say is "it has responded as expected to treatment!"
I'm in UK and find that the best stage 4 get here is "stable". Which I'm happy to take!!
It will be interesting to see if anyone has info on reduced treatments.
I did ask last year when my scans were excellent if less treatments were possible but the answer from my Oncologist was "don't know".
Juls
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Old 06-02-2016, 06:50 AM   #2
Hopeful
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Join Date: Aug 2006
Posts: 3,380
Re: My Onc wants to stretch out Herceptin infusions

Here is a link to an abstract about the clinical pharmacology of Herceptin: http://www.ncbi.nlm.nih.gov/pubmed/18690878

It states the half-life of Herceptin as 28 days. The half-life of a substance is the period of time required for the concentration or amount of drug in the body to be reduced by one-half.

So, at 21 day intervals, you are maintaining a somewhat higher overall concentration of Herceptin in the body than at 28 day intervals. Neither is long enough for the drug to be completely out of the body.

Hope this is helpful.

Hopeful
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