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Old 11-26-2014, 11:11 AM   #27
rhondalea
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Join Date: Jun 2011
Location: Somerset, NJ
Posts: 487
Re: Cognitive Rehabilitation

I edited my post. Thanks for the nudge that made the light go on. Aricept is an acetylcholinesterase inhibitor not an anti-cholinesterase inhibitor. I still have these moments, and one of the side effects of topiramate is worsened memory. (I can handle that if I can function, but sometimes the results are weird.)

I can't tolerate benedryl, period. Ever.

But I think that it's possible to have higher levels of choline in the brain after chemo without having higher levels of choline in the body. That's been demonstrated with a lot of chemicals that act as neurotransmitters but are also present elsewhere, generally. As choline levels rise, serotonin levels fall. I believe there may be other consequences, but I don't have them to hand.

Exercise didn't help me at all. If I did manage to get myself up and active, it put me down for the count for at least a day or two or more afterward. It was terrible. Now, I'm able to take a daily walk again without a problem, so maybe I'll be able to go back to the gym soon.

The written schedule seems to be the tool of choice. She printed out daily pages from Outlook for me. I resisted because I have Outlook, and I'd rather do everything on the computer, but there's something to be said for a notebook that you can scribble in. You just have to be careful to allow yourself enough time and enough breaks.
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2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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