new target identified for her2+ breast cancers resistant to dual targeting with

[Lani]

breast cancer is a disease that metastasizes early--even before a lump can be detected.

According to the stem cell "theory" of breast cancer (the cancer stem cells have been identified, and I for one, no longer consider it a theory as the facts seem to support it) those cells sit quiescently,dormantly, not dividing in the bone marrow and once "re-awakened" are the source of recurrence/distant metastasis.