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Old 03-23-2014, 08:26 PM   #4
Jean
Senior Member
 
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
Re: determining which patients benefit from more than 5 years of antihormonal therapy

Hi Becky like you this is my 9th year on AI (Femara)
being Estrogen 90%
highly Her2 positive
OncotypeDX was high also ....so for me it was not requiring brain surgery to continue on Femara past 5 yrs.
My concern is next year....after yr.10

http://www.medicalnewstoday.com/releases/274300.php?tw

From article:

"We are about to start a trial called IBIS-3 of extended therapy with aromatase inhibitors in long-term survivors with ER+ breast cancer with other unfavourable characteristics, and also adding new drugs used in other conditions that show promise in preventing breast cancer recurrence - a bisphosphonate (bone sparing drug) and metformin (diabetes drug). Hopefully, this biomarker work will help to pinpoint more accurately which patients need additional treatment."

I am thinking I woud like to take part in this trial.
I am seeing my onc. early April and will discuss this but I am fairly certain i will hear that "we just don't know"
What are your thoughts Becky?
Hugs dear sister,
Jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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