attn: Rolepaul, Marvass et al Review article on IT herceptin stresses need 4 ClTrial

[evlin75]

I have not totaled Susan's Herceptin mg. but she started at 20 per week in July of 2012. After about a month she went to 40 per week and the last few months 80 per week. Then progression forced the start of Depocet IT that cannot be mixed with Herceptin so the 80 is given IT every other week.
The progress has been up and down with each MRI . Overall progress better the last one but some extra tumor growth in the lower spine. The meningitis effect of the depocyt caused them to have to introduce dexamethasone each treatment and some each day to keep the inflammation under control.
The perjeta was not controlling the total body tumor problems so that was stopped and she is now on TDM1 every three weeks.
Her ambulation is difficult and she is weak from the methods used to treat her and the disease.
Radiation is being considered to zap the larger area in the lower spine. A repeat MRI will be done soon to help them make that decision.
Each persons make up is different and so the reaction to the treatments will be different, but we battle on to try to cope with the twists and turns of this disease.
My best to all who are dealing with this.
We are trying Emend now to cope with the nausea. It is also beneficial as it crosses the blood /brain barrier to help destroy tumor cells in the brain.