Several large studies have established the addition of "trastuzumab to chemotherapy as the gold standard in early breast cancer that overexpresses HER2. Little is known about the role of such adjuvant treatment in node-negative subcentimeter tumours ('small tumours', pT1a/b) because these patients were generally excluded from the pivotal trials." MAYBE if my Mother "Sheila" would have been able to receive Herceptin when she was diagnosed >IV she wouldn't be where she is now....Woulda, coulda, shoulda....It's all expost Facto now.
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