Herceptin or Tykerb ?

[alex1]

Tykerb / Xeloda not working
15 Aug 2011 – Oral chemotherapy started – Tykerb 250, Xeloda 500
28 Feb 2012 – PET-CT Scan –hepatic metastasis,lymphatic
metastasis,skeletal metastasis

I.V. 3 weekly chemo started PacliALL given as suggested by Onco . What are other options ?


_________________________________________________
Age 38 years
17 Feb 2010 – Mammography – Mass in right breast suspicious of malignancy
19 Feb 2010 – FNA from right breast – Duct carcinoma cells seen
04 Mar 2010 – Right radical modified mastectomy – tumor 3X3X2, LN1/19 +ve
15 Mar 2010 – Hormone receptor – ER negative, PR negative, c erb B2 –
positive score3
25 Mar 2010 – Detection of HER-2/neu by FISH - positive
1 Apr 2010 – Chemotherapy Started – 3 CEF + 4 Docetaxel + Herceptin (3wkly X 17)
30 May 2011 – Course of Herceptin completed
9 Aug 2011 – CT Scan – focal lesion 3.2X2.9cm in segment IV of liver
10 Aug 2011 – PET-CT Scan – solitary hepatic metastasis, precaval LN
suspicious mets
15 Aug 2011 – Oral chemotherapy started – Tykerb 250, Xeloda 500
28 Feb 2012 – PET-CT Scan –hepatic metastasis,lymphatic
metastasis,skeletal metastasis

[Becky]

See if your doctor will keep you on the Tykerb but add in Herceptin with a chemo. I think you need to reconsider Herceptin.

[Jackie07]

The article below gives an overview of different treatment options:

"Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer."
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251862/?tool=pubmed