OH what to do???

[Lani]

No, pertuzumab is a very large molecule, like herceptin and does not cross the blood-brain barrier normally.

If you have leptomeningeal metastasis, intrathecal herceptin has been tried (Courtney had it, I believe, among others). Boswellia serata has been tried for l-m mets as well. Try using the search function above for leptomeningeal metastasis I know I have posted several articles about treatments in the past

Good luck!