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Old 04-12-2010, 12:24 PM   #1
Cal-Gal
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Location: Los Angeles, CA
Posts: 309
Re: Herceptin and CA 27.29 tumor marker

Thanks Weety-

I think you are right--that I have 'high-end' normal values-or at least I hope you are on the right track--

I dont have my marker pre-surgery-just post surgery/ pre-chemo which was also 27.

Looks like we are in same boat--my chemo completed about 6 mo prior to yours-I am still on Herceptin as well--

I am looking forward to ending Herceptin in 8 weeks and seeing if they drop even further--

Thanks for taking the time to reply--
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DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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Old 04-15-2010, 03:54 PM   #2
Chelee
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Location: Southern, CA
Posts: 2,511
Re: Herceptin and CA 27.29 tumor marker

CalGal,
After seeing all your TM'ers results I would not be concerned at all. Your markers were on the higher side to start with. I see the only time they had an upwards trend was during your chemo & that does happen. One thing I'd like you to note too is that TM'ers are not reliable for everyone. For some ppl they just do not work at all. But when they do work...you want to look for a slow or rapid increase. (Like mine climbed very slowly for a yr & not once did they go back down.) I see your TM'ers bounce around a bit. I wouldn't be worried at all if my markers were like yours...honestly I wouldn't. That seems to your "normal" range.

As long as your markers continue to bounce around in consistent range like they are...I would rest easy. Again, remember that TM's don't work for everyone. TM'ers can be stressful as you know...and since they aren't always reliable many onc's refuse to even use them. Why stress the patient out. I hope this helps.

Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 04-16-2010, 01:18 PM   #3
COOK12151
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Wink Re: Herceptin and CA 27.29 tumor marker

Hi, my ca 27.29 marker was 33, and I didnot get any treatment.
Can you tell me what does that mean.


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