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It is a test co-marketed by Genentech that measures the amount of Her2 protein. You can measure for Her2 by measuring overproduction of protein or look to see how many copies of the Her2 gene are present. Both are viable but the protein is at least showing you make too much protein (which is the go-go button). For example, perhaps you have millions more copies of the Her2 gene but if they are non-productive, then they don't make protein and it is just a mutated mutation.
Some people may disagree with me but its the protein that counts more (and it may be why Herceptin works in some women who are Her2 neg - they don't have an excessive gene count but what's there produces too much protein).
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Hybrid Mode
