her2 copy number cut-off point (by FISH) may be decreased (2.2to1.5)

Assuming that being Her-2 positive, a copying ratio above the current point of 2.2 per FISH and that being Her-2 positive correlates with a more "aggressive" tumor, would it be logical the higher the copying ratio, the more "aggressive" tumor? Also, if so, would it be logical, the higher the copying ratio, the more "receptors" Herceptin may have to connect with, thus rendering Herceptin even more effective? Any studies done on this?