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Old 05-12-2008, 04:57 PM   #1
Lori R
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Join Date: Jan 2008
Location: Evergreen, Colorado
Posts: 454
Robin,
I replied to another thread of yours as another liver enzyme watcher.

I am very pleased that your Drs are performing tests to make sure that they figure the trend out.

I too had elevated liver enzymes coming off of 6 rounds of Taxotere + Herceptin. It seemed odd that while I was on all of the super strength drugs that the enzymes were fine. But...they rose by about 30 points 2 months after the chemo completion. This lasted for 2 rounds of testing. Not certain why, but they recently settled themselves down.

What is a hidascan?

Please don't fret too much if you have to have a liver biopsy. When then told me I was going to have one early in this journey it sounded HORRIBLE. Maybe I still still in a shock but I did not find the procedure to be too painful. It sounds worse than it is.

I am certainly behind you..cheering you on....Lori
__________________
2007
Oct - Diagnosed - Stage IV
5 c.m. IDC - Left Side er/pr- Her2+++
Node + 2/14 - Single Liver Met
Double Mastectomy
Nov - Begin T+H
2008
Feb-Complete 6 cycles- T&H- NED
March - Continue - Herceptin Only
April - Rads for 6 weeks
2009
Continue Herceptin - Continue NED
April - Recurrance- 3 cm. Liver Met
May - Cryosurgery
June - November - Abraxane + Herceptin
Aug - PET/CT - CTC = 0 Back to NED
2010
January - Continue NED
July - Recurrance - 3 cm Liver Met CTC=1
August - Cryosurgery #2
August - November Navelbine
November - Back to NED - End Navelbine
2011
Feb - Recur - 4 cm Liver Met - Same Left Lobe
March Surgery it is -Couldn't get a clean margin
July - Confirmed continued liver involvement
August - Begin Herceptin + Tykerb
October - Mixed results from H+T
Add Abraxane + H + T - Nov - April
2012
January PET Scan - It's working!!
April - Back to NED
July - Recurrance
August - Begin TDM-1 Trial (Taxol + TDM-1)
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Old 06-02-2008, 10:41 AM   #2
ElaineM
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Posts: 3,142
liver enzymes

Hi,
I had elevated liver enzymes the first time I took Adrainmycin and Taxotere in 2000, but they went back to normal after one or two weeks. I would speak up and check it out though. Better to be safe than sorry.
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Old 06-03-2008, 06:42 AM   #3
robint
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Join Date: Dec 2007
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all the test have been negative to date, Enzymes still high, alk phos, alt,ast,now billirubin is elevated slightly, testing every week and going up about 30 points each time no drugs for 6 weeks. frustrated for we are at to possibilities, toxic liver that may have damaged a portion and continuing to progress or mets that are not obvious on ct. I cannot have mri, for expanders
i think we will repeat ultra sound. we are waiting to see if they will trend down, then schedule biopsys.

thanks
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Old 06-18-2008, 09:21 AM   #4
Gina
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Location: Alexandria, VA
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Exclamation What was the outcome of this?

Very interested to know how you are doing now. Have your doctors checked to see if your bile duct is being blocked by a stone or is inflamed with bacterial infection?

Not to worry, if it is the bile duct, they will put in a stent and you will be FINE and all the liver enzymes will normalize and the Alk phos and the bilirubin will go down. However, get on it, as if you don't --the bilirubin will build and you will turn yellow all over and risk liver failure if your liver enzymes approach 800 ALERT...

fyi,
Gina
Gpopp@Comcast.net
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