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			05-11-2008, 06:37 PM
			
							
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			#1
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2007 
				Location: Mississippi 
				
				
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				Spider bite
			 
			 
			
		
		
		
		Hi y'all. I have been lurking lately. I have been busy in the garden and everytime I planted a flower I thought of Michelle. I am trying to find a "real job" with benefits so I have been getting my resume together and also getting my art website up. I have also had problems with phlebitis in my right arm that seems to be connected with, first tamoxifen, and then arimidex. Will be starting coumadin so that I can try to take arimidex again. The phlebitis gets in the ways of me typing.  
 
Then Friday night a brown recluse bit me on my right shoulder. I killed the spider and then found the bite. I spent several hours Sat. at the emergency room because I had a systemic reaction. I developed a rash all over and my face was beet red and swelling. I had no idea how bad it could hurt. I am still taking bendryl and medrol, and it helps some. I am just hoping that it doesn't make the lymphedema worse. My shoulder feels like someone hit me with sledge hammer. I am also hoping that I avoid the flesh destroying aspects of this. The nurse came into the room right before I went home and told me my wrinkles in my forehead were coming back. Then she said that in this case it was a good thing. It helps to see the humor. 
 
I am still NED as of my last test and so very thankful for it. When things start getting to me I remind myself of how much worse things are for so many of you and how y'all get through it all with lots of love and humor and strength and it helps me past the dark side of all of this. Thanks. 
 
Leslie 
		
	
		
		
		
		
		
		
			
				__________________ 
				In the world of destiny, there are no statistics. 
Jan. 26- mammogram and ultrasound- suspicious lump 
Mid-February- lumpectomy, infiltrating ductal carcinoma ~4.5 cm and a 1 cm DCIS, did not get clear margins, did not check lymph nodes 
ER+/PR+, her2 +++, nuclear grade 3 of 3 
February 20-PET scan showed something on liver. No biopsy. 
March- Started carboplatin, herceptin, taxol on a four week cycle 
May 3- Pet scan, with intent to do a biopsy, found nothing, liver or breast- no biopsy because there is nothing to biopsy 
June 21- new onc, very concerned that there had been no biopsy,  
June 18th-CAT scan, bone scan-negative 
August 7th - Brain MRI-negative 
August 9th- mastectomy, all pathology negative 
January 2008 still NED! New oncologist -herceptin for full year after chemo- until July, and tamoxifen---negative scans since May '07 
July 2008-Finished Herceptin!
			 
		
		
		
		
		
		
	
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			05-12-2008, 02:47 AM
			
							
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			#2
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Feb 2007 
				Location: Paris, France 
				
				
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		Hi Leslie, 
you seem to be having a hard time with lymphoedema.  You really did not need this bite. I have a different type of problem with my arm so I cannot help. Ladies, did you ever have such a terrible reaction?   
  
I hope to see your art website soon!  
Michka 
		
	
		
		
		
		
		
		
			
				__________________ 
				08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20% 
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex 
 
12.2010 Mets to liver,Herceptin+Tykerb 
03.2011 Liver resection ER+70% PR- 
04.2011 Herceptin+Navelbine+750mg Tykerb 
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum 
11.2011 Pet clear. Stop Navelbine,  continuing on Hercpetin+Tykerb+Aromasin 
02.2012 Mets to lungs, nodes, liver 
04.2012 TDM1, Ned in 07.2012 
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems 
04.2016 Liver mets. Back on Kadcyla 
08.2016 Kadcyla stopped working. mets to liver lungs bones 
09.2016 Biopsy to liver. no more HER2, still ER+ 
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife 
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere 
02.2017 30 micro mets to brain breathing getting worse and worse 
04.2017 Liquid biopsy/CTC  indicates HER2 again. Start Herceptin with Halaven 
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
			 
		
		
		
		
		
		
	
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			05-12-2008, 05:20 AM
			
							
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			#3
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Aug 2006 
				Location: Poland Ohio just a little south of Youngstown. 
				
				
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		 Oh my gosh, Leslie, that's terrible. One more thing that you didn't need. I don't know about you but I'm scared to death of spiders, don't know how you mustered the courage to kill it. I'll bet this is the one and only time you were glad to see those wringles (lol). I'll keep you in my prayers. 
Hugs 
		
	
		
		
		
		
		
		
			
				__________________ 
				Susan 
Age: 61 
dx: 5/25/06 
2 cm/ 0 nodes 
Lumpectomy rt breast on 7/26/06 
ER/PR- / Her2+++ 
A/C x 4 
finished taxotere 2/07 
finished 33 rads  
Herceptin finished 12/07/07 Yippee!
			 
		
		
		
		
		
		
	
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			05-12-2008, 07:25 AM
			
							
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2006 
				Location: Wilmington, Del. 
				
				
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		 Thank you.  It's a reminder to all of us who have our hands in the flower and vegetable beds. 
		
	
		
		
		
		
		
		
			
				__________________ 
				MJO 
  
IDC, Stage I, Grade 2 
Oncotype DX Score 32 
Her2++ E+P+, Node Neg. 
Lumpectomy 11/04/05 Clear Margins 
3 Dose dense AC (Couldn't tolerate 4) 
4 Dose dense Taxol & Herc. (Tolerated well) 
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score) 
2 years of Arimidex, then three years of Femara 
Finished Femara May 2011  
			 
		
		
		
		
		
		
	
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			05-14-2008, 12:58 PM
			
							
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			#5
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2007 
				Location: Mississippi 
				
				
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		 The spider bite is better. Now the area on my arm that they kept saying was phlebitis may be MRSA (methycillin resistant staph), of course nobody agrees on anything so I am taking Bactrim and waiting to see if it goes away. They couldn't culture it, because it is not on the outside. I usually have a lot of pain when it appears but not this time. Maybe the prednisone is keeping the swelling down. By the way, I was in bed when I was bitten. The lymphedema is usually confined to two fingers and part of my hand but occasionally my arm starts swelling. But I am better. Thanks, everyone. 
		
	
		
		
		
		
		
		
			
				__________________ 
				In the world of destiny, there are no statistics. 
Jan. 26- mammogram and ultrasound- suspicious lump 
Mid-February- lumpectomy, infiltrating ductal carcinoma ~4.5 cm and a 1 cm DCIS, did not get clear margins, did not check lymph nodes 
ER+/PR+, her2 +++, nuclear grade 3 of 3 
February 20-PET scan showed something on liver. No biopsy. 
March- Started carboplatin, herceptin, taxol on a four week cycle 
May 3- Pet scan, with intent to do a biopsy, found nothing, liver or breast- no biopsy because there is nothing to biopsy 
June 21- new onc, very concerned that there had been no biopsy,  
June 18th-CAT scan, bone scan-negative 
August 7th - Brain MRI-negative 
August 9th- mastectomy, all pathology negative 
January 2008 still NED! New oncologist -herceptin for full year after chemo- until July, and tamoxifen---negative scans since May '07 
July 2008-Finished Herceptin!
			 
		
		
		
		
		
		
	
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			05-14-2008, 06:00 PM
			
							
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			#6
			
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			 Senior Member 
			
			
		
			
			
			
				 
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				Location: Carmel, Indiana 
				
				
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		 Yikes, I hope you get better soon.  Wishing you well, 
Beth 
		
	
		
		
		
		
		
		
			
				__________________ 
				DX 9-19-07 at age 40 
DCIS, Inv. Duct. Car. 3 cm 
Positive lymph node biopsy 
Er+Pr+Her+++ 
Carboplatin/Taxotere/Herceptin 
10-1-07 -- 1-16-08 
Herceptin every 3 weeks until 9/24/08 
Lump. and node dissection 2-12-08 
BRCA1 and 2 negative 
30 rads finished 4-23-08 
oophorectomy 5-6-08 
Femara started 5/25/08 
Zometa for osteoporosis every 6 mo. started 9-24-08 
  
Married 16 years! 
3 kids - daughter (10), twin sons (7)
			 
		
		
		
		
		
		
	
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			05-14-2008, 06:12 PM
			
							
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			#7
			
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				Join Date: Aug 2007 
				Location: Stayton, Oregon 
				
				
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		 MRSA can be nasty.  Stay on top of it.  Hope they make up their minds soon and you get the proper treatment.  Nana Karen 
		
	
		
		
		
		
		
		
		
		
		
	
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			05-14-2008, 06:40 PM
			
							
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			#8
			
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		 Hi Lesli, 
  
You've had a lot to deal with lately between MRSA and the spider bite. A few years ago, one of my brothers was bitten in the leg by a brown recluse spider (or as his son would say: but not reclusive enough). He did have skin necrosis and needed a port in his arm and antibiotics. It finally cleared up and he is fine now. He had no other reaction. 
  
I'm glad though that you're still NED! 
  
Joan 
		
	
		
		
		
		
		
		
			
				__________________ 
				Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2023 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!! 
			 
		
		
		
		
		
		
	
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			05-14-2008, 07:09 PM
			
							
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			#9
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2007 
				Location: Mississippi 
				
				
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		 If they are right, and if you know my story, you have reason to know that I am not all that trusting of doctors, it makes sense. I ended up staying in the hospital for 2 extra days because of a low grade fever they never explained and I have had fever and chills off and on since my mastectomy. I also had a lot of pain in my hips that they couldn't explain. I have had this outbreak on my arm several times now. I am not through with this. From what I read there is a blood test they can do and I am going to request it. In the meantime I will take my Bactrim and wait for it to get better. what got me is the doctor trying to say this was probably a community associated infection rather one I contracted in the hospital. I have been in and out of hospitals and doctors offices for a year and a half now. And good old medicaid has decided that I have no more doctors visits until July. I am so frustrated with the system. 
 
Leslie 
		
	
		
		
		
		
		
		
			
				__________________ 
				In the world of destiny, there are no statistics. 
Jan. 26- mammogram and ultrasound- suspicious lump 
Mid-February- lumpectomy, infiltrating ductal carcinoma ~4.5 cm and a 1 cm DCIS, did not get clear margins, did not check lymph nodes 
ER+/PR+, her2 +++, nuclear grade 3 of 3 
February 20-PET scan showed something on liver. No biopsy. 
March- Started carboplatin, herceptin, taxol on a four week cycle 
May 3- Pet scan, with intent to do a biopsy, found nothing, liver or breast- no biopsy because there is nothing to biopsy 
June 21- new onc, very concerned that there had been no biopsy,  
June 18th-CAT scan, bone scan-negative 
August 7th - Brain MRI-negative 
August 9th- mastectomy, all pathology negative 
January 2008 still NED! New oncologist -herceptin for full year after chemo- until July, and tamoxifen---negative scans since May '07 
July 2008-Finished Herceptin!
			 
		
		
		
		
		
		
	
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			05-18-2008, 02:02 AM
			
							
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			#10
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Nov 2007 
				Location: Connecticut 
				
				
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		 Oh, sweetie, you have had so much to deal with, and now, the spider bite.  As you know, the Brown Recluse bite is no joke.  Please know that you're in my thoughts and prayers.  Love, Bill 
		
	
		
		
		
		
		
		
		
		
		
	
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			05-18-2008, 12:00 PM
			
							
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			#11
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2007 
				Location: Mississippi 
				
				
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		 I feel ashamed complaining (whining) when so many of you are sicker than I am. I told my doctor once that I knew I wasn't his sickest patient but that I was going to do everything I could not to become that patient. It just seems that some of the problems I am having now are more the results of them not listening or not paying attetion or just being wrong. Of course the spider bite does not fall into that category. Thanks for listening. 
 
Leslie 
		
	
		
		
		
		
		
		
			
				__________________ 
				In the world of destiny, there are no statistics. 
Jan. 26- mammogram and ultrasound- suspicious lump 
Mid-February- lumpectomy, infiltrating ductal carcinoma ~4.5 cm and a 1 cm DCIS, did not get clear margins, did not check lymph nodes 
ER+/PR+, her2 +++, nuclear grade 3 of 3 
February 20-PET scan showed something on liver. No biopsy. 
March- Started carboplatin, herceptin, taxol on a four week cycle 
May 3- Pet scan, with intent to do a biopsy, found nothing, liver or breast- no biopsy because there is nothing to biopsy 
June 21- new onc, very concerned that there had been no biopsy,  
June 18th-CAT scan, bone scan-negative 
August 7th - Brain MRI-negative 
August 9th- mastectomy, all pathology negative 
January 2008 still NED! New oncologist -herceptin for full year after chemo- until July, and tamoxifen---negative scans since May '07 
July 2008-Finished Herceptin!
			 
		
		
		
		
		
		
	
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			05-18-2008, 07:39 PM
			
							
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			#12
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Jan 2008 
				Location: "Love never fails." 
				
				
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		 I was bitten by some tiny bugs during chemotherapy last fall.  The redness crept all the way to my elbow in 3 days.  Luckily we went to the doctor on the 4th day and I was put on IV with antibiotic right away.  It took another 10 days worth (or 2 weeks?) of oral antibiotic to clear the infection.  And that's when I started the lymphedema treatment - wrapped up in gauze - now wearing compression glove and sleeve.   
  
Hope you feel better soon.  It does require patience. 
		
	
		
		
		
		
		
		
			
				__________________ 
				Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html 
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2
 
NICU 4.4 LB
Erythema Nodosum 85 
Life-long Central Neurocytoma 4x5x6.5 cm  23 hrs 62090 semi-coma 10 d PT OT ST 30 d 
3 Infertility tmts 99 > 3 u. fibroids > Pills 
CN 3 GKRS 52301 
IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen 
Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET 
6 TCH Cellulitis - Lymphedema - compression sleeve & glove 
H w x 4 MUGA 51 D, J 49 M
Diastasis recti
Tamoxifen B. scan 
Irrtbl bowel 1'09 
Colonoscopy 313 
BRCA1 V1247I 
hptc hemangioma 
Vertigo 
GI - > yogurt 
hysterectomy/oophorectomy 011410 
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk 
DEXA 1/13
1-2016  lesions in liver largest 9mm & 1.3 cm onco. says not cancer. 
3-11 Appendectomy - visually O.K., a lot of puss.  Final path result - not cancer. 
Start Vitamin D3 and Calcium supplement (600mg x2)  
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016 
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior.  Due to possible adenocarcinoma, Recommend annual surveilence. 
7-10-2019 CT to check lung nodule. 
 1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
 "I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa
 
Advocacy is a passion .. not a pastime - Joe
			 
		
		
		
		
		
		
	
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			05-19-2008, 07:38 AM
			
							
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			#13
			
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				Join Date: Apr 2006 
				Location: Wilmington, Del. 
				
				
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		 I was working in the garden yesterday and felt a sting.  I now have a swollen right eye.  Talk about taking my own advice!!   I'm sure I'll be fine but it's a comfort to know that I have a checkup with my family doctor on Thursday.  Some little bug was angry at me for pulling up its weed home. 
		
	
		
		
		
		
		
		
			
				__________________ 
				MJO 
  
IDC, Stage I, Grade 2 
Oncotype DX Score 32 
Her2++ E+P+, Node Neg. 
Lumpectomy 11/04/05 Clear Margins 
3 Dose dense AC (Couldn't tolerate 4) 
4 Dose dense Taxol & Herc. (Tolerated well) 
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score) 
2 years of Arimidex, then three years of Femara 
Finished Femara May 2011  
			 
		
		
		
		
		
		
	
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			05-19-2008, 09:25 AM
			
							
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			#14
			
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			 Senior Member 
			
			
		
			
				
			
			
			
				 
				Join Date: Apr 2007 
				Location: Mississippi 
				
				
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		 When they wrapped my arm my blood pressure started climbing so that pretty much eliminates the sleeve. So far, it is better. I believe the swelling and pain in my arm may have been something else. I am taking coumadin now and that may help. I really had made my mind up to stop the arimidex and my oncologist talked me out of it for now.  
 
MJo, The garden is worth the bugs, isn't it. My bite is getting better. I hope yours is. We are gardening on a shoestring this year but I had a lot of plants that I had rooted and some to divide so we made a new bed anyway. We put up a Martin house last year but a Great Crested Flycatcher moved in instead. Shes back this year with friends.  And we have lots of tiny tomatoes. I LOVE our garden. A garden teaches delayed gratification so well. The world would be a better place if everyone gardened. 
 
Leslie 
		
	
		
		
		
		
		
		
			
				__________________ 
				In the world of destiny, there are no statistics. 
Jan. 26- mammogram and ultrasound- suspicious lump 
Mid-February- lumpectomy, infiltrating ductal carcinoma ~4.5 cm and a 1 cm DCIS, did not get clear margins, did not check lymph nodes 
ER+/PR+, her2 +++, nuclear grade 3 of 3 
February 20-PET scan showed something on liver. No biopsy. 
March- Started carboplatin, herceptin, taxol on a four week cycle 
May 3- Pet scan, with intent to do a biopsy, found nothing, liver or breast- no biopsy because there is nothing to biopsy 
June 21- new onc, very concerned that there had been no biopsy,  
June 18th-CAT scan, bone scan-negative 
August 7th - Brain MRI-negative 
August 9th- mastectomy, all pathology negative 
January 2008 still NED! New oncologist -herceptin for full year after chemo- until July, and tamoxifen---negative scans since May '07 
July 2008-Finished Herceptin!
			 
		
		
		
		
		
		
	
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			05-19-2008, 10:10 AM
			
							
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			#15
			
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				Join Date: Jun 2006 
				Location: San Antonio, TX 
				
				
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		 You know what, Leslie, that is a great thought about "if everyone gardened!  I think you may just be right on!  Glad that you are better.  Thanks for making time to share with us.  ma 
		
	
		
		
		
		
		
		
			
				__________________ 
				MA in TX. 
Grateful for each and every day.... 
  
Diag. 12/05 at age 60 
Stage II, Grade 3, 4.5 cm primary tumor 
ER/PR- Her2 +3 strongly positive 
Her2 by FISH 7.7 amplified 
vascular invasion 
Ki67 20% borderline 
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew 
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive  
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense) 
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense) 
Radiation & Herceptin Jan. 22 - March 1, 2007 
Finished Herceptin Dec. 10 '08! One extra year. 
Port removed August, 2012. 
8 1/2 years since diagnosis! 5 1/2 Years NED!
			 
		
		
		
		
		
		
	
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			05-19-2008, 10:36 AM
			
							
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			#16
			
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			 Senior Member 
			
			
		
			
			
			
				 
				Join Date: Sep 2005 
				Location: OH 
				
				
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				Oh Leslie
			 
			 
			
		
		
		
		you are so strong!  I probably would have had a heart attack if I found a brown recluse on me -- especially in bed.  I don't even do well with potato bugs...I'm glad to read that you are getting better.  I'm happy you, and others, get so much out of gardening.  Where I live we are overrun with deer, coyotes, and the occasional fox, so gardens arent' done as easily.   Take care and I hope you find the position and benefits you're looking for. 
		
	
		
		
		
		
		
		
		
		
		
	
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