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Old 01-27-2008, 07:19 AM   #1
GemmaG
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Sorry to hear about your mom. T/X didn't work for me,too. I'm on weekly Herceptin/Navalbine since October of last year (weekly herceptin and two weeks on/one week off navalbine). My scans this month showed no new disease. Hopefully, this combo will do the works.
My love to you all.

Hugs,
Gems
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Old 01-27-2008, 06:05 PM   #2
supermehra
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Gemma, thanks that is very encouraging. What is your her2, er, pr status? Did your doctor talk to you about Tykerb+Herceptin? My mother has a brain lesion and herceptin does not penetrate the brain, hence concerned about that. Carboplatins are next i guess.
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Old 01-28-2008, 07:58 AM   #3
Rupali
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I talked to my onc abt Herceptin and Tykerb and he said as they are running the Neo ALTO trial so there has to be some clinical evidence to start the trial.
Plus if you see logically Tykerb + Herceptin should give a double punch to kill the cancer cells from inside and outside.

He was very confident abt it and my onc is the Director of Research for a big hospital in Boston.

Regards,
Rupali
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Old 01-28-2008, 04:11 PM   #4
Vanessa
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I am currently on Herceptin/Tykerb/Abraxane. I have an brain MRI scheduled for tomorrow to see if the combination worked. I have been on Herceptin since June, 2006. My doctor did not take me off it when she added the Tykerb. I hope it is a good combination. Good luck to your mom. I will keep both of you in my prayers.
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Old 01-29-2008, 06:35 AM   #5
supermehra
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Vanessa thanks. The big concern for us is that the Brain lesion has come back despite Tykerb which was the molecule supposed to traverse the BBB. Our onco feels that since it has failed, no point continuing with it. I guess we need to reassess that.
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