Progression free survival vs overall survival

IRENE FROM TAMPA · 12-28-2007, 10:54 AM

I have been taking Avastin since Sept with the Tykerb, but since I now progressed to two "more" tumors he thought time for change.

I am on B/P meds since Oct. so far seems to keep it a bit lower. I always ran normal also but went up to around 139/89 where it seems to stay although last weeks reading was 114/78????? Thas was unusual even for me.

Do you think that the Avastin along with the Herceptin could cause added b/p issues? I was on Herceptin for 6 1/2 years some time back and I did notice that my pressure always ran a little higher then norm for me. Other then that, everything else was fine with my muga scans.

I guess I will see how I do. Its has been a few years now since I have tried the Herceptin.

Thanks Sheils

Sheila · 12-28-2007, 11:46 AM

Irene
I think I forgot to mention my mets are in my lymph nodes in the neck area...just like Lolly....my B/P has always been 110/60....even with Herceptin, but it kept climbing since the Avastin and was running 180/88 even with meds....I could feel it going up...anyway, after being off 1 month it is 145/78 with meds, so maybe it was the combo with the Herceptin and Avastin....I am just glad its going down!

StephN · 12-28-2007, 12:14 PM

Hi Girls -
My friend here took Avastin with Abraxane (NO Herceptin). Her blood pressure skyrocketed before it was over. She took this combo for about 3 or so months. Stopped the Avastin first, then the Abraxane.

She reported last week that she is now OFF the blood pressure meds after stopping the Avastin a little over a year ago. So, this does seem to self correct with time as can the LVF drop from Herceptin. Her underarm nodes are also still under control. So, I hope that is a good omen for you, Sheila.