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Old 12-04-2007, 07:43 AM   #1
nitewind
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Location: Poland Ohio just a little south of Youngstown.
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Hi Joannie, Boy, can I relate to everything you're saying.
I've been on prozac for nine years. At the start, I had that lump in my throat too. Had the scope done and they found nothing. My primary care doc set me up with a psych doc. He put me on prozac, a very light dose at first. Now I'm on 60 mg. a day, he also prescribed Xanax for those times when I was having the panic really bad. Both meds really saved me. I believe that if it's something that you need, by all means, take the meds. I hated the way I felt before the meds, and I couldn't explain the feeling to anyone. Nothing is more important than your mental health. Over the years that I've taken the prozac, I've probably gained about 40 lbs, but I can think now, my mind is clear and that nasty lump in my throat is long gone.
You just need to make a decision, I know that putting on the weight is bad, but truthfully, if I had to put on another fifty pounds, it would be worth it to me to keep my sanity.
Good luck to you and I'll keep you in my prayers.
Hugs
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Susan
Age: 61
dx: 5/25/06
2 cm/ 0 nodes
Lumpectomy rt breast on 7/26/06
ER/PR- / Her2+++
A/C x 4
finished taxotere 2/07
finished 33 rads
Herceptin finished 12/07/07 Yippee!
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Old 12-04-2007, 09:46 AM   #2
Jade
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Hi Joannie

I'm another one who completely relates to what you're saying. I have been through H-E-double hockeysticks with antidepressants so have learned a thing or two along the way. Hopefully my story will help in some way. I know how bad those bad days can be.

I started Prozac in 1998 for PMDD (pre-menstrual dystrophic disorder - PMS off the scale!). I wore a T-shirt that said "I have PMS and a gun - any questions?". 6 years and 20 lbs later I stopped Prozac when I went into chemopause, as my doctor had told me I'd probably need it until then. I weaned myself off in a few weeks with no problems whatsoever.

Then came the brutal hot flashes, back to back, day and night. Doctor gave me Effexor, said it can reduce hot flashes by 60%. Started 75mg, increased to 150. First few months the hot flashes were noticeably less, but then I started to have serious symptoms which at the time I was unaware were caused by Effexor. I thought my ill health was due to all the surgery, chemo, ongoing Herceptin and then to ice the cake a really unfortunate bout of Giardia (aka beaver fever LOL! - a water-borne bacteria similar to E-coli - think stagnant water from a beaver dam). But I'd been treated and was cured from the giardia. Long story short, I ended up being rushed to hospital dehydrated and
severely ill. You see, all the years I took Prozac there were no problems, if I forgot to take them for a few days everything was still okay. Not so with Effexor - the pills need to be taken at the same time every day or the patient begins withdrawal. The most obvious symptom is "brain freezes" or "jolts" or "shocks". So not knowing all this, I missed taking my pills for about 3 days and went into withdrawal, complete with back to back brain freezes, severe vomiting and diahrrea, to the point I was hospitalized. They checked me for Giardia bacteria - all clear. It was then that I started to research Effexor and understood what I was dealing with. Nevertheless I prevailed (anything to keep those crippling hot flashes at bay) with a new discipline for taking the medicine every 24 hours. I still had brain freezes almost every day. Then the hot flashes were increasing; it seemed like the Effexor was not working as well. Then the worst thing: I gained almost 20 pounds, and it was like it happened overnight! Now I had lower back pain, joint pain and looked and felt like the Stay-Puft marshmallow man. Not so funny was the fear caused by the bone pain - of course I thought the cancer had come back in the bones. I was freaking out, I have to say! I went on the Internet and read again all the horror stories about Effexor, this time focussing on the weight gain aspect, and decided that minute that I would begin to wean off. It took another 3 1/2 months before the brain jolts completely stopped, and about the same time before the added 20 lbs. was gone.

At the same time as the Effexor horror ended, another began. I started to mentally spiral down into a very very dark place. Although physically I was getting better, dealing with the fallout from cancer together with a number of other major stresses brought me to the point where I could no longer cope. My oncologist described it as having experienced a personal 9/11. I was advised that I needed medication to correct this chemical imbalance that I had, there was no other way I would get better (believe me, I'd been trying to do everything I could to keep myself healthy so I wouldn't need medication).

So now I'm on Wellbutrin. Joannie, you are right when you mentioned about the seratonin as Wellbutrin only works on dopamine, does nothing to increase seratonin. It's true, there is no weight gain, no brain freezes, so that's a plus. But I now have regular anxiety, which I've never had before. It was very bad the first few weeks of Wellbutrin, then tapered off. I hate the anxiety. I know I also need the seratonin, but I have researched my head off and there simply is not an antidepressant that will increase seratonin levels without causing weight gain. I went into my local clinic recently to have my Wellbutrin prescription renewed. My regular doc wasn't in so I saw a different one and his first comment to me was "tell me, does this stuff work at all for you?" His feedback was that Wellbutrin was useless for the majority of people who try it. I told him I was about 60% better than before but was now full of anxiety. He also confirmed my research that there simply is no antidepressant for us seratonin-challenged people that will not cause weight gain.

Sorry for the long post. I keep thinking there has to be an answer but so far I haven't found it. I agree with the others' advice to see a psychiatrist as they are more knowledgeable of these medications and their use than regular GPs. I hope you find some peace and soon.

All the best,
Jade
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Dx Nov.04 - Stage 1, Grade 3, widespread high grade DCIS, Paget's disease of nipple, 8mm tumor invasive DC (ductal carcinoma), ER/PR-, HER2+++
Nov.04 - left mast., clear margins, 6 of 6 nodes clear
Feb.05 - began EC chemo, 4 rounds (every 3 weeks)
Aug.05 - began Herceptin every 3 weeks for 1 year
Aug.06 - ended treatment
NED
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Old 12-04-2007, 03:00 PM   #3
Joannie
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Thanks for all of your responses. I too did great on the Celexa and then Lexapro. I was very reluctant to wean myself off of it but because I kept asking my doc about it, she thought I owed it to myself to try getting off. She said it would take about a month before I would know whether my body was producing the seratonin that I needed. I truly believe that there is some chemical imbalance. Now that I'm on Wellburtin, she said it would take about two weeks for it to begin to work. It has just been over two weeks. Maybe I'm just being impatient!

As far as seeking help with a mental health professional, I actually did that right after I finished chemo. Was the best thing I ever did. I began taking the anti-depressant while I was seeing him. I went to several appts. with him, probably over the course of 8 months. Time and money well spent. I wish that option would have been recommended to me during treatment!

I can honestly say, the everyday life crap that got to me on a day to day basis before cancer, didn't affect me after cancer. I thought it was just new perspective. I'm sure some of it was that, however, I now am convinced that the anti-depressent played a huge role in my overall ability to cope with all that I had been through. Most things I just let roll off my back but I don't seem to be able to do that right now. In the last two days, my chest has been tight, stress in my shoulers and back is getting worse and overall mood is just poor. My husband thinks I should call the doc and get back on Lexapro. I don't know what is worse, the bad moods or being overweight!
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Diagnosed April 2003
3.3 cm tumor left breast
HER2 positive 3++
ER/PR negative
Masectomy April 2003
4 Rounds of AC - dose dense
4 Rounds of Taxol - dose dense
Removed right breast prophalactically
Full reconstruction with implants/nipples
No Late Herceptin Received
Started Tykerb TEACH Trial in May 2007
Completed Tykerb TEACH Trial in May 2008
5 year NED August 27, 2008!!!
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Old 01-15-2008, 02:28 PM   #4
MCS
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Question

I've been place on only 5mg of lexapro a day. I'm scared of taking antidepressants.

I am not really noticing any improvement. I would like to feel that I can handle things and have them not affect me.

I don't know what's worse anxiety or depression or what came first?

do you take ativan to get rid of the anxiety?

what do you really feel when you're on this stuff?

I'm also worried about weight gain, since I'm only about 5' tall!

love

maria
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Old 01-15-2008, 02:28 PM   #5
MCS
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Question

I've been place on only 5mg of lexapro a day. I'm scared of taking antidepressants.

I am not really noticing any improvement. I would like to feel that I can handle things and have them not affect me.

I don't know what's worse anxiety or depression or what came first?

do you take ativan to get rid of the anxiety?

what do you really feel when you're on this stuff?

I'm also worried about weight gain, since I'm only about 5' tall!

love

maria
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Old 01-15-2008, 03:09 PM   #6
MCS
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ANYWAY

was the weight gain automatic result of taking these? or was it that your apppetite increased as result of the seratonin intake?

thanks to all

love

maria
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Old 01-15-2008, 09:27 PM   #7
Catherine
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Lexapro

I took 10mg Lexapro for 18 months and it was great for me. I was able to wean off. Sorry to be in a hurry....off to bed.

All the best....and good luck, Catherine
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Found my own lump in the shower
April 2006 at the age of 58
Stage IIB, ER- PR- HER2+++ multi focal tumors, largest 2.3cm
Chemo first: AC/Taxol over 16 weeks
Bilateral mastectomy Sep 06
33 rads after the surgery
1 year of Herceptin completed Dec 07
15 years and no recurrence as of April 2021
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Old 01-15-2008, 11:54 PM   #8
Jade
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Hi Catherine,

Did you gain weight while on Lexapro? Did it help with anxiety or was that not an issue for you?
Thanks in advance for your reply,
Jade
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Dx Nov.04 - Stage 1, Grade 3, widespread high grade DCIS, Paget's disease of nipple, 8mm tumor invasive DC (ductal carcinoma), ER/PR-, HER2+++
Nov.04 - left mast., clear margins, 6 of 6 nodes clear
Feb.05 - began EC chemo, 4 rounds (every 3 weeks)
Aug.05 - began Herceptin every 3 weeks for 1 year
Aug.06 - ended treatment
NED
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