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Old 11-27-2007, 10:52 AM   #1
Jean
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Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
Extremely Exciting News...

Lani,
in a study such as this when would trials begin on humans? How many years out?

Thx,
Jean
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Arimidex 5/05
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Oncotype DX test 4/17/06, 31% high risk
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Old 11-27-2007, 04:38 PM   #2
Lani
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Gene therapy per se has been talked about for twenty

or thirty years and only this year is really seeing any success in very few cases in a few diseases.

If the therapy can be done epigenetically(by altering methylation or acetylation of genes or histones) with drugs already in development or already approved, I would guess less than five years (but what do I know?)

I need to read further into this...
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Old 11-27-2007, 04:41 PM   #3
Lani
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if it involves bone marrow transplantation

the question is if you need to destroy the host bone marrow first (fraught with lots of complications) and what type of graft vs host disease might develop
madubois is an expert on that, it seems!
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Old 11-27-2007, 04:43 PM   #4
Lani
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If you are talking about trials of trying to inject it into the

ovum of a human and then see how the next generations come out, I think it will take a long time --lots of ethical questions, paperwork, etc involved

let alone the question of it would work
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Old 11-28-2007, 11:24 AM   #5
Lani
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our new mascot???

http://news.bbc.co.uk/2/hi/health/7116675.stm
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