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Old 11-12-2007, 04:19 PM   #1
R.B.
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Join Date: Mar 2006
Posts: 1,843
Balancing your omega threes and ensuring adequate intake of long chain omega threes DHA and EPA should assist neurological function.

At the most basic level neurons need DHA. Women have higher neuron density. Women have a higher DHA requirement.

Babies are DHA hoovers and may deplete a mothers brain DHA. Some women's brains do shrink in pregnancy.

This is a search of the NCBI library on DHA and depression. I have copied below as the list of trials is more powerful than any explanation I can give.

You may also be interested in the `Greek Diet' thread which looks at omega three and six and BC etc.

A trial in France where they looked at breast fat tissue at the same times as lump excisions produced the result that women in the highest third for DHA EPA fats in breast tissue had a 70% lower risk of the lumps being invasive.

If you click on the link below you will find the trial links below and more.

RB

http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder.

"Deficits in DHA concentrations were greater in female MDD patients (-32%) than in male MDD patients (-16%), and could not be wholly attributed to lifestyle factors or postmortem tissue variables......
CONCLUSIONS: These results demonstrate a selective deficit in the omega-3 fatty acid DHA in the orbitofrontal cortex of patients with MDD [major depressive disorder]. This finding adds to a growing body of evidence implicating omega-3 fatty acid deficiency as well as the orbitofrontal cortex in the pathophysiology and potentially pathogenesis of MDD."



http://www.ncbi.nlm.nih.gov/sites/en...pression%20dha




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Old 11-12-2007, 05:17 PM   #2
Andrea Barnett Budin
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Location: LAND OF YES! w/home in Boca Raton, Florida Orig from L.I., N.Y. Ever hovering IN THE NOW...
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Exclamation Which Came First...

Okay before the anti d/anti anxiety med came the stress! So, is the culprit the cortisol overload (naturally prodced), a hormonal imbalance (pre or post menopausal, pregnancy) or the anti d eventually taken? I go w/stress beyond the norm (we all experience a degree of pressure in Life) as being the root of all illness, striking your genetically weakest body part. There's the link again. The mindbody connection. T cell counts go down as depression sets in, compromising the immune system and leaving you virtually defenseless...
Andi
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Andi BB
'95 post-meno dx Invasive LOBULAR w/9cm tumor! YIKES + 2/21 nodes. Clear mammo 10 mnths earlier. Mastec/tram flap reconst/PORT/8 mnths chemo (4Adria/8CMF). Borderline ER/PR. Tamoxifen 2 yrs. Felt BLESSED. I could walk and talk, feed and bathe myself! I KNEW I would survive...

'98 -- multiple mets to liver. HER2+ 80%. ER/PR- Raging, highly aggressive tumors spreading fast. New PORT. 9 mnths Taxotere Fought fire w/fire! Pronounced in cautious remission 5/99. Taxotere weekly for 6 wks, 2 wks off -- for 9 mnths. TALK ABOUT GRUELING! (I believe they've altered that protocol since those days -- sure hope so!!)
+ good old Vit H wkly for 1st 3 yrs, then triple dosage ev 3 wks for 7 yrs more... The "easy" chemo, right?! Not a walk in the park, but not a freight train coming at 'ya either...

Added Herceptin Nov '98 (6 wks after FDA fast-tracked it for met bc). Stayed w/Vit H till July '08! Now I AM FREE! Humbly and eternally grateful for this life-saving drug! NED since '99 and planning on keeping it that way. To hell w/poor prognosis and nasty stats! STOPPED VIT H JULY '08...! REMAIN STABLE... Eternally grateful...Yes is a world & in this world of yes live (skillfully curled) all worlds ... (e e cummings) EVERY DAY I BEAT MY PREVIOUS RECORD FOR # OF CONSECUTIVE DAYS I'VE STAYED ALIVE. Smile KNOWING you too can be a miracle. Up to me and God now...
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Old 11-12-2007, 05:31 PM   #3
Brenda_D
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I was never on any type of anti-depressant before BC.
I am on Prozac now, because of the BC.
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12/12/06- IDC Stage III, 4x A/C, 35 rads, Herceptin 1 year
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Old 11-12-2007, 05:38 PM   #4
R.B.
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Stress undoubtedly chemically links in at lots of levels but DHA moderates the stress response production of norepinephrine etc.

So I would put lack of DHA / omega three as a risk factor.

I was unaware stress impact on T cell function I will look that up.

Thanks Andi BB

RB
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