Her2/ most inherited type of BC?

[Joanne S]

This is the same topic as last month's post:

click: Inheriting HER2+ ???

Joanne S

[AlaskaAngel]

Could some of this non-BRCA bc have an epigenetic basis?

I know that since my BRCA results came back (negative), there have been other genetic pieces of the puzzle ferreted out. Myriad stated on the results that as time went by if other types were identified, they would contact me....

Since I have one aunt who died of bc mets to the brain I wonder if hers was HER2 positive, but she died many decades ago. No one else in the family died of bc, and all lived fairly long lives or are still living without recurrence. Which, again, makes me wonder why risk is not considered in regard to the longevity/recurrence of those in the family who have had bc?

A.A.

[Karen W]

Hi AA,

As I have mentioned in earlier posts, I am the 12th person on my mom's side of the family to get bc. In your post you mentioned something about your aunt dying of brain mets and wondering if she was her2+. My aunt died from mets to many different places, one of which was the brain and she was triple negative.

She was dx with mets right when Herceptin was approved for use in women with mets. I think her doc was hoping that she was her2+, so he could use Herceptin.

Karen