I read mixed reviews on the postmenopausal use of HRT after BC. It appears that the lower the dose, the more bio-identical the formulas are, and the lower the duration of therapy, the less risk of increased bc mortality. Additionally, the progesterone with estrogen increases risk. Also, cyclic progesterone rather than continuous MAY be safer.
The oncologists tell me that f you're hormonal negative, it is okay to keep menstrating and not take an anti-estrogen. So that makes me wonder if you are hormonal negative, wouldn't logically HRT seem okay? It's all complex. I know that the HABITS trial indicates that HRT increases bc risk. However, other trials indicate that HRT doesn't increase bc, ad some trials even indicate that HRT has lower risks than no use, which seems odd. I do think what stage you were at diagnosis effects the outcome of HRT use. I certainly don't see any risk associated with something as low stage as DCIS with masectomy, which essentially has no risk of relapse. I don't know about higher stages, though. All I can say, is the results are mixed and can make comprehension of it all VERY difficult.
GREAT ARTICLE ON HRT:
http://www.cbs.com/cbs_cares/menopau...chiff_02.shtml
Tibolone, a European Drug, and another Pharmaceutical Alternatives to HRT :
http://www.health.harvard.edu/newswe...n_tibolone.htm
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