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Grace,
When I was briefed to sign the consent forms for Herceptin infusions at my onc's, they pointed out that I might experience ankle swelling, and, if so, to report it to my onc and they will prescribe a diuretic for it. You should ask your onc about this symptom and see if they will give you a medication for it. Fortunately, I have not had this experience, but I recall posts from others who had and got the water pill and were fine afterwards. Best of luck to you.
Hopeful
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