Prescribing Herceptin

juanita · 12-12-2006, 06:47 PM

Mine was right at 1 cm, grade 3, er/pr-, her2+, no node involvement. My onc automatically started me on herceptin as soon as I finished chemo, which was like a week after they made it available without being in a study.

Bev · 12-12-2006, 09:30 PM

I don't know if there is a protocol yet as it was approved last month. You have IDC which means some cancer cells could be circulating looking for somewhere else to create havoc. Herceptin has few side effects but only works for about half of HER+. Your grade may tell you if you should persue more treatment. Get more opinions. The downside is they might want to combine it with a chemo agent to make it more effective. Only you can decide. If you can get Herceptin alone, I would do it. I think I would do it also if you had to do it with taxol.

Also if you are ER/PR neg, you have more limited treatment options, which would make Herceptin look like a very good choice. Good luck, BB

Jean · 12-12-2006, 10:38 PM

I had a small tumor (one size does not fit all) do not decide based on tumor size alone, rather decide on the character of your tumor, is it high risk, what is the grade and what is the KI67 levels, as I said, I had a small tumor 6mm prior to
biopsey and 3mm when lumpectomy was done, but it was high risk for recurrance and was node neg. It is favorable to have node neg. and small tumor catching the beast early, but Her2 likes to travel, I would consult with additional dr. - treatment has changed much this past year. I did decide to have chemo/herceptin ..

Wishing you the best.

Jean

penelope · 12-12-2006, 11:13 PM

Me too! I had a 7mm node negative tumor and had chemo and herceptin. I finish in January. Herceptin is easy to take.

MJo · 12-13-2006, 12:50 PM

I was stage 1 with a .5 CM tumor and node neg. My Oncotype DX score was 32 -- the beginning of high risk. I took Herceptin. My impression is that Her2 cancers, no matter how small, always score "high intermediate" or "high" risk of recurrence in 10 years on the Oncotype DX test. My guess is that in the future the question will not be whether or not to take Herceptin (or Tykerb) if we are Her2, but how long to take Herceptin.