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Old 11-18-2006, 10:26 AM   #1
Cheryl E
Senior Member
 
Join Date: Sep 2005
Posts: 26
I had 3 oncs tell me to have ovarian suppresion in order to take an AI because the outcome was much better. Although estrogen production can be suppressed in the ovaries by drugs or removal, your adrenal glands still produce estrogen. Thus, the reason for AIs. For me, the choice was easy, as my husband and I knew we were done having kids. I was 40. Actually, it was a relief since my hubbie was too chicken to get a vastectomy. I received 2 rounds of Lupron shots while my body recovered a bit from chemo and breast reconstruction. The oopherectomy was sooooo simple. Up and moving, slowly, the next day. Able to attend a girl's weekend (with dr permission) the next week! That was 3 years ago. About a year ago, I began Vagifem due to vaginal dryness and atrophy. Hot flashes are minimal and no muscle pain/stiffness. I,too, exercise/stretch every day. I am on Femara. My mom is also on femara (although Her2-) without issues.

Cheryl
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Old 11-19-2006, 05:54 AM   #2
VirginiaGirl
Senior Member
 
Join Date: Oct 2006
Location: Fredericksburg, VA
Posts: 93
ElaineRyan - I started Tamoxifen in Sept 06 as I was premenopausal, and then had an oophorectomy in October. My onc said then to stay on Tamoxifen for now, but I'm meeting with him tomorrow for a consult to review where we are, and I plan to ask him to put me on an AI instead, probably the Arimidex since there's been so much positive info about it. Will let you know what he says!

God Bless!
__________________
Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin

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