Lapatinib/Xeloda dosing

Sheila · 10-14-2006, 12:27 PM

Ken

If she has side effects, they may want to decrease the Xeloda...I am on the Xeloda with Herceptin and I take 1500mg in the a.m. and 1000 mg at night....they have found that more is not better with Xeloda.....Lolly takes less, but takes it continually...I take it 14 days and off 7. So far no problems....Sandy might be able to answer since she is on Tykerb and Xeloda.

Sandy H · 10-14-2006, 04:01 PM

I take 1250 mgs of Tykerb in the morning on an empty stomach every day(no break). I started out taking Xeloda 3000 mgs a day (1500 a.m and 1500 p.m.) but 9 days on it I had diarrhea so bad my potassium dropped and I was starting to have atrial fib with my heart. Took a two week break and dropped the dose to 2000 mgs. I still have bouts of diarrhea lots of gas but its manageable so far. The Xeloda needs to be taken with food and I drink lots of water. I hope this helps we are all different and so each has to try it for themselves. hugs, Sandy

Lolly · 10-14-2006, 08:08 PM

Ken, I'm not on a trial and my Xeloda dose is very low, 500mg am & pm with no break, along with Herceptin 2 weekly. Although I've had no side effects from this low dose, we recently added radiation as the response from the low dose was not what we hoped for.

mkrny · 10-14-2006, 11:20 PM

Thanks for the input. I'll keep a close eye on Maryann's tolerance for the xeloda. I'll have make sure we get potasium rich foods for her:

http://whfoods.org/genpage.php?tname=nutrient&dbid=90