Has anyone ever used Etoposide or VP-16??

[Amy]

Hi,
Have any of you wonderful women ever used Etoposide or VP-16 in your chemo regimen??? This is the drug my Onc is recommending now, but I haven't heard very much about this drug being used for Her 2 metastatic BC. So far I've not responded to anything, completely that is, and it's difficult to say how much, if at all the chemo I've been given staved off progression. I've had A/C, Taxol, Herceptin, Xeloda and Navelbine. And I haven't been on anything for 2 1/2 months now due to tumor progression and decreased heart EF. It was my choice to not proceed with anything for a bit....you know that quote, "Insanity is doing the same thing over and over again expecting different results". Well, that was my mindset at the time. I thought maybe if I "cleaned up" my body from the toxic chemo that it might make a difference. Nope, still progressing. Now, I need to do somehting. I'm leaning toward a combo of Gemcitabine and Carboplatin.....my Onc is not familiar with Lapatinb at all which disappointed me. I'm hoping to get on some form of treatment that will hopfully keep me stable until more info on lapatinib is available after the ASCO meeting. Does anyone know when or if it will be available off label??? Any comments will be much appreciated.
Love and prayers,
Amy