Liver?

[RhondaH]

Ever since I started Herceptin 8/05, I have had liver issues. Hepatic failure is listed as one of the "rare" side effects of Herceptin. When I first started Herceptin, my liver enzymes began raising (not sure if due to Herceptin or the Phenobarb I take for seizures as this TOO can increase liver enzymes). November, I had severe pain in my upper right side (gall bladder was taken out 2001) so went to ER and hospital did cat scan of liver and chest xray, everything ok (I was dx Stage 1, ER/PR-, Her2+, no nodes 2/1/05, did 6 rounds of dose dense TEC, 33 rads and began 1 yr of Herceptin every 3 weeks 8/18/05, will be done 8/10/06). Doc put me on every week Herceptin to see if this would bring enzymes down, apparently did. Didn't like doing every week (wanted normalcy) so asked doc if could do every 3 again. He said sure and that it was safe to say the Herceptin was affecting my liver. Not my LAST Herceptin, but the one before a coworker noticed that my hands and feet (looks like a glove, much like when I was going through chemo, but not red) were yellow (but no where else on my body). The yellow comes and goes. Last week I was feeling a bit nauseas (not bad, but a little), but TODAY I feel VERY nauseas. Yesterday, I noticed my one leg is slightly swollen, and I have been itching a bit (this also comes and goes) as well as my right side and back hurt on and off (this may be because of tubing w/ Tony at the water park). I just feel kind of poopy (don't need this as I move in 2 weeks). Also, I haven't had an ECHO since 8/15/05 (my doc is "lenient" about that, my onc nurse said). I PRAY, that this is not mets to the liver, but I was wondering if anyone else had the Herceptin cause a "liver irritation"? I hate feeling like a hypochondriac, but I hate the alternative. Take care and God bless.

Rhonda