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Old 02-07-2006, 08:05 PM   #1
Barbara
Senior Member
 
Join Date: Oct 2005
Location: Payson, Arizona
Posts: 96
Increasing Serum HER2 Test Results - Should I Panic

I am looking for advice. I am Stage 2B and my Serum Her 2 test has gone from 5.5 in September, to 9.8 in November and is now 12.2 in January. The Serum Her2 neu lab test that I have run has a normal range of 5.1-13.5. I am now close to the upper level. During this time my CA 27-29 has been 9, 13, 20, 9, 10, 13 and 14. The CA 27-29 is run about every 3 weeks. Over the last two years since my diagnois my CA 27-29 has ranged up and down between 9 and 26 so I see nothing alarming in the CA 27-29. My last CEA was in November and it was .6. I am really worried about the Serum HER2 test as everthing I have read about early stage cancer says a medium of 254 days was found for 64% of the early stage patients from the time the Serum HER2 went over 12 and mets were present clinically.

I see my oncologist on Monday. I was thinking of asking him to repeat the Serum HER2 and do a CEA as a CA 27-29 was drawn today. Then if the Serum Her2 test remains high and or if my CEA is up I would like to ask for a pet scan and Brain MRI. If they come back clean I would like both repeated in three or four months (I am thinking of the medium time of 254 days to clinical mets after the Serum HER2 reaches 12).

What advice do you have for me? Should I be in a panic? Have any of you had this high of a Serum HER2 and did not have mets in the next seven months? I know many of you know far more than I do about both these tests and what may be a good course. I am presently receiving Herceptin infusions every three weeks.

Thank you for any advice you may offer.

Barbara
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