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Old 12-27-2005, 04:41 AM   #1
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Herceptin and the Heart ... Need help

Hi. I was initially dx 08/02 ... invasive ductal carcinoma with dcis ... lumpectmy and radiation. In 04/05 I was dx with lymph node cancer ... same side reoccurrence, 2 out of 16 nodes positive. anxillary dissection, 3 months A/C every 3 weeks, 3 months Taxol/Herceptin weekly. HER2NEU 3+, Elston grade 3, hormone negative, comedo necrosis. I begain triple dose Herceptin 12/19/05 every 3 weeks for 9 more months. I had a reaction the very first dose of Herceptin/Taxol in August. I was there 9 hours that day and they had to give me injections to counter-act the reaction and then continued with the treatment. The reaction was chills, body aches. On 12/20/05, The day after the triple dose of Herceptin alone, I was really ill ... chills, body aches ... flue like symptoms.

My muga scan before Taxol/Herceptin was LVEF 75% .... after 3 months of Taxol/Herceptin it was 50.5%. After the first triple dose Herceptin I began to notice breathing issues .... getting out of breath on exertion and I have been very tired. On 12/25/05 I noticed little pockets of water retention/swelling in my feet and my feet feel more numb then they did after the Taxol. I called the docs office yesterday and they put me on a dieuretic for water retention via a phoned in prescription.

Has anyone else had issues like this while on Herceptin and is it cause to be worried?

Thank you,
Diana
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