Zometa Trials

Hi:

I am a Stage IIB, ERPR - and Her2 positive patient who has been accepted into the Pilot Study to Evaluate the Efect of Zoledronic Acid (Zometa) on Occult Malignant Bone Marrow Cells in Patients with High Risk Early Stage Beast Cancer.

I feel torn as whether to participate in the Trial as I recall that the large study in Finland showed that Hormone negative patients had poorer outcomes when they received Bisphosphonates in early stages. I know the smaller English study showed positive results but it did not break patients down by Hormone or Her2 status.

Do any of you have more current information on the positive or negative affects of Bisphosphonates in early Her2 breast cancers? I need to make up my mind shortly. Thanks.